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In the CY 2025 PFS proposed rule, we stated that in light of the AMA's current data collection efforts and because the methodological and data source changes to the MEI finalized in the CY 2023 PFS final rule would have significant impacts on PFS payments, similar to our discussion of this topic in the CY 2024 PFS rulemaking cycle (88 FR 78829 through 78831), we continue to believe that delaying the implementation of the finalized 2017-based MEI cost share weights for the RVUs is consistent with our efforts to balance payment stability and predictability with incorporating new data through more routine updates

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Furthermore, [Difen Injection is designed for "flexible-dosing-utility." It is available in potassium salt forms for "immediate-release," which is ideal for a sudden toothache or migraine, and sodium salt forms for "delayed-release," which provides a steady level of medicine for chronic back pain

Potential Side Effects & Safety Profile Transparency is crucial when discussing peptides